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| Player | Status | Injury | Practice | Plays | Updated | Owned By |
|---|---|---|---|---|---|---|
| DE Nick BosaSF | OUT | Knee | DNP · DNP · DNP | — | Oct 17 | |
| LB Drake ThomasSEA | OUT | Ankle | DNP · DNP · DNP | — | Oct 14 | |
| S Derwin James Jr.LAC | OUT | Hamstring | DNP · DNP · DNP | — | Oct 16 | |
| QB Lamar JacksonBAL | OUT | Ankle | DNP · DNP · DNP | — | Oct 16 | K K-Bo Ghosts |
| RB Jeremiyah LoveARI | OUT | Ankle | DNP · DNP · DNP | — | Oct 16 | S Straight Bums Homie |
| RB Saquon BarkleyPHI | OUT | Hamstring | DNP · DNP · DNP | — | Oct 16 | J J-Rod the Bod |
| RB Breece HallNYJ | OUT | Quadricep | DNP · DNP · DNP | — | Oct 16 | T Three Stripe Life |
| LB Kaden EllissNO | OUT | Calf | DNP · DNP · DNP | — | Oct 16 | |
| WR Rashee RiceKC | OUT | Hamstring | DNP · DNP · DNP | — | Oct 16 | TThree Stripe Life |
| S Talanoa HufangaDEN | OUT | Ankle | DNP · DNP · DNP | — | Oct 14 | |
| S Kevin Winston Jr.TEN | OUT | Quad | DNP · DNP · DNP | — | Oct 16 | |
| RB Kyle MonangaiCHI | OUT | Thumb | DNP · DNP · DNP | — | Oct 16 | M Make-A-Wish Project |
| LB T.J. EdwardsCHI | OUT | Hamstring | DNP · DNP · DNP | — | Oct 16 | |
| WR Deebo Samuel Sr.SF | OUT | Hamstring | DNP · DNP · DNP | — | Oct 17 | T The Sharknado |
| RB Jacory Croskey-MerrittWAS | OUT | Groin | DNP · DNP · DNP | — | Oct 17 | B Beats by JJ |
| S Jalen PitreHOU | OUT | Shoulder | DNP · DNP · DNP | — | Oct 16 | |
| WR Jordyn TysonNO | OUT | — | — | Oct 11 | KK-Bo Ghosts |
|
| S Antoine Winfield Jr.TB | OUT | Rib | DNP · DNP · DNP | — | Oct 16 | |
| RB David MontgomeryHOU | OUT | Groin | DNP · DNP · DNP | — | Oct 16 | C Captain Scurve |
| QB Jalen HurtsPHI | OUT | Calf | Full · DNP · DNP | — | Oct 16 | B ButtHoleTrolls |
| WR Adonai MitchellNYJ | OUT | Finger | DNP · DNP · DNP | — | Oct 16 | R Reading Dwayne Bowe |
| WR Tre' HarrisLAC | OUT | Hamstring | DNP · DNP · DNP | — | Oct 16 | |
| LB Jalyx HuntPHI | OUT | Knee | DNP · DNP · DNP | — | Oct 16 | |
| RB Zach CharbonnetSEA | OUT | Knee | Limit · Limit · Limit | — | Oct 14 | CCaptain Scurve |
| RB Dylan SampsonCLE | OUT | Knee | DNP · Limit · Limit | — | Oct 16 | C Cream of the Crops |
| LB Carson SchwesingerCLE | Questionable | Ankle | DNP · DNP · Limit | 70% | Oct 16 | |
| WR Chris OlaveNO | Questionable | Illness | DNP · DNP · Limit | 95% | Oct 16 | TThe Sharknado |
| LB Josiah TrotterTB | Questionable | Knee | -- · -- · Limit | 69% | Oct 16 | |
| S Budda BakerARI | Questionable | Rest | DNP · Full · DNP | — | Oct 16 | |
| WR Mike EvansSF | Questionable | Ribs | DNP · DNP · DNP | 64% | Oct 17 | SStraight Bums Homie |
| S Kam CurlLAR | Questionable | Ankle | -- · Limit · DNP | 69% | Oct 16 | |
| WR A.J. BrownNE | Questionable | Ankle | Limit · Limit · Limit | 95% | Oct 17 | TThree Stripe Life |
| RB Quinshon JudkinsCLE | Questionable | Ankle | DNP · DNP · Limit | 69% | Oct 16 | BBeats by JJ |
| WR DJ MooreBUF | Questionable | Shoulder | DNP · DNP · Limit | 73% | Oct 16 | CCream of the Crops |
| S Nick CrossWAS | Questionable | Illness | Full · Full · Full | 69% | Oct 17 | |
| DT Mason GrahamCLE | Questionable | Knee | DNP · DNP · Limit | 27% | Oct 16 | |
| LB Daiyan HenleyLAC | Questionable | Knee | Limit · Limit · Limit | 81% | Oct 16 | |
| WR DK MetcalfPIT | Questionable | Illness | -- · -- · DNP | 100% | Oct 16 | MMake-A-Wish Project |
| WR Stefon DiggsWAS | Questionable | Hamstring | DNP · Limit · Limit | 55% | Oct 17 | MMake-A-Wish Project |
| TE Tyler WarrenIND | Questionable | Groin | -- · -- · Limit | 80% | Oct 16 | JJ-Rod the Bod |
| QB Caleb WilliamsCHI | Questionable | Hamstring | Full · Full · Full | 67% | Oct 16 | SStraight Bums Homie |
| DE Abdul CarterNYG | Questionable | Calf | DNP · DNP · Limit | 71% | Oct 16 | |
| DE Jaelan PhillipsCAR | Questionable | Hamstring | Limit · Limit · Full | 88% | Oct 16 | |
| RB TreVeyon HendersonNE | Questionable | Ankle | Limit · Limit · Limit | 48% | Oct 16 | SStraight Bums Homie |
| LB Christian EllissNE | Questionable | Chest | Limit · Limit · Full | 96% | Oct 16 | |
| TE Kenyon SadiqNYJ | Questionable | Concussion | Limit · Limit · Full | 95% | Oct 16 | JJ-Rod the Bod |
| RB Alvin KamaraNO | Questionable | Back | Limit · Limit · Limit | 72% | Oct 16 | S Sam's Town |
| RB Rico DowdlePIT | Questionable | Toe | Limit · Full · Full | 83% | Oct 16 | BButtHoleTrolls |
| LB Zaven CollinsARI | Questionable | Hip | -- · -- · DNP | 69% | Oct 16 | |
| TE Pat FreiermuthPIT | Questionable | Calf | -- · -- · -- | — | Oct 17 | MMake-A-Wish Project |
| WR Ja'Kobi LaneBAL | Questionable | Wrist | Full · Full · Full | 75% | Oct 16 | RReading Dwayne Bowe |
| RB Tyjae SpearsTEN | Questionable | Knee | Limit · DNP · Full | 96% | Oct 16 | RReading Dwayne Bowe |
| RB Sean TuckerTB | Questionable | Quad | DNP · Limit · Limit | 43% | Oct 16 | TThe Sharknado |
| DE Montez SweatCHI | Suspended | — | — | Oct 18 | ||
| LB Dre GreenlawSF | Suspended | — | — | Oct 18 | ||
| DE James Pearce Jr.ATL | Suspended | — | — | Oct 18 | ||
| LB Micah ParsonsGB | PUP | — | — | Oct 18 | ||
| DE Myles GarrettLAR | IR | — | — | Oct 18 | ||
| RB Travis Etienne Jr.NO | IR | — | — | Oct 18 | SSam's Town |
|
| RB Jordan MasonMIN | IR | — | — | Oct 18 | TThe Sharknado |
|
| WR Alec PierceIND | IR | — | — | Oct 18 | RReading Dwayne Bowe |
|
| TE Terrance FergusonLAR | IR | — | — | Oct 18 | ||
| RB Jadarian PriceSEA | IR | — | — | Oct 18 | SStraight Bums Homie |
|
| RB Jonah ColemanDEN | IR | — | — | Oct 18 | KK-Bo Ghosts |
|
| RB Jonathon BrooksCAR | IR | — | — | Oct 18 | MMake-A-Wish Project |
|
| RB Tank BigsbyPHI | IR | — | — | Oct 18 | JJ-Rod the Bod |
Practice: DNP = did not participate, LP = limited, FP = full, in order for the week's practices so far. Plays is FantasyPros' estimated chance of playing.
There's reportedly "optimism" Baker Mayfield will return in Week 7 against the Panthers.
Fantasy impact: Mayfield didn't practice this week, but he resumed throwing on Monday. His status will need to be monitored in practice next week.
Colts WR Alec Pierce is still a few weeks away from a return to game action.
Fantasy impact: Pierce was able to get out of his cast earlier this week. He remains week-to-week.
Packers EDGE Micah Parsons still isn't practicing yet.
Fantasy impact: The earliest Parsons may return is Week 9 according to Tom Pelissero. The Packers will play at least a few games without him.
Jacory Croskey-Merritt has been ruled out for Monday's game against the 49ers.
Fantasy impact: Croskey-Merritt was unable to practice this week. Rachaad White and Austin Ekeler will lead the Commanders backfield.
Stefon Diggs is listed as questionable for Monday's game against the 49ers.
Fantasy impact: Diggs returned to practice on Friday. He'll be a game-time decision on Monday, but he seems to be trending in the right direction.
The Steelers placed Roman Wilson on injured reserve.
Fantasy impact: Wilson injured his finger last week. He will miss at least the next four games.
Marcus Mariota has been ruled out for Monday's game against the 49ers.
Fantasy impact: Mariota will miss his second straight game. Athan Kaliakmanis will continue to serve as the primary backup to Jayden Daniels.
The Patriots activated A.J. Brown from injured reserve.
Fantasy impact: Brown will make his return for the first time since Week 1. He'll be a WR2 with some risk in his first game back for fantasy managers.
Deebo Samuel Sr. has been ruled out for Monday's game against the Commanders.
Fantasy impact: Samuel will miss at least one game as expected. He remains week-to-week.
Mike Evans has been listed as questionable for Monday's game against the Commanders.
Fantasy impact: Evans was unable to practice through Friday. He will be a game-time decision on Monday.
Christian Kirk has been listed as questionable for Monday's game against the Commanders.
Fantasy impact: Kirk could make his return from injured reserve. We likely won't know his status till Monday.
Ja'Kobi Lane (wrist) has been activated from IR, clearing the way for him to return against Cleveland.
Fantasy impact: Lane has been out since fracturing his wrist in Week 1, so it will be interesting to see what his snap counts and route shares look like after the IR stint. The team praised him all offseason and focused on him during his brief playing time in Week 1, so hopefully he will be able to find himself a decent role as the WR2 of the offense.
Caleb Williams (hamstring) is the starter for the Bears on Sunday against the Falcons. After a few weeks' absence, the franchise QB is back.
Fantasy impact: Williams was initially questionable to play, but the Bears are now planning on getting him back in the lineup after a week of practice where he took starter reps. It will be interesting to see Caleb in a more "regular" game and how it affects the pass catchers, who have only played with Caleb in one normal game, and even that "normal" game saw copious amounts of production from the running backs.
Jalen Hurts (blood clot) has been placed on IR due to a blood clot.
Fantasy impact: At first the Eagles were not going to place him on IR, but after further consultations, they have decided to make that move. Tanner McKee will start in his place for at least the next four games, with Carolina on tap tomorrow. All the pass catchers will likely see a downtick in production, but should still be usable if McKee is halfway decent.
Pat Freiermuth has been added to the injury report as questionable for Sunday's game against the Buccaneers.
Fantasy impact: Freiermuth was a late addition to the injury report with a calf injury. His status will need to be monitored Sunday morning.
DK Metcalf is off the injury report for Sunday's game against the Buccaneers.
Fantasy impact: Metcalf had been listed as questionable with an illness. He'll be good to go with the Steelers wide receiver room depleted.
Mykel Williams was limited in practice on Friday.
Fantasy impact: Williams will need to be monitored in practice on Saturday ahead of Monday's game against the Commanders.
James Thompson Jr. was officially limited in practice on Friday.
Fantasy impact: Thompson will need to be monitored in practice on Saturday ahead of Monday's game against the Commanders.
Upton Stout was limited in practice on Friday.
Fantasy impact: Stout will need to be monitored in practice on Saturday ahead of Monday's game against the Commanders.
Siran Neal was limited in practice on Friday.
Fantasy impact: Neal will need to be monitored in practice on Saturday ahead of Monday's game against the Commanders.
Colton McKivitz was limited in practice on Friday.
Fantasy impact: McKivitz will need to be monitored in practice on Saturday ahead of Monday's game against the Commanders.
Garret Wallow missed practice on Friday.
Fantasy impact: Wallow remains week-to-week.
Marques Sigle missed practice on Friday.
Fantasy impact: Sigle will need to be monitored in practice on Saturday ahead of Monday's game against the Commanders.
Gracen Halton did not practice on Friday.
Fantasy impact: Halton will need to be monitored in practice on Saturday ahead of Monday's game against the Commanders.
Free agent Terrell Jennings worked out for the Patriots on Friday.
Fantasy impact: Jennings was one of three running backs to work out for New England.
Elijah Arroyo underwent further testing on Friday.
Fantasy impact: Arroyo suffered the injury in Thursday's game against the Broncos. There should be an update on him by next week.
The Lions placed Ben Bartch on injured reserve with a foot injury.
Fantasy impact: Bartch will be sidelined for at least the next four weeks.
Tytus Howard (knee) will play in Sunday's game against the Baltimore Ravens.
Fantasy impact: Howard missed practice earlier in the week due to a knee issue, but it's no longer an issue for him and won't prevent him from playing in Week 6. Cleveland's offensive line will be stronger with him in the lineup against Baltimore.
Tylan Wallace (knee) will be available to play in Sunday's game against the Baltimore Ravens.
Fantasy impact: Wallace will be good to go on Sunday, despite being listed with a knee injury at practice earlier in the week. He is unlikely to be fantasy relevant for the foreseeable future, however.
Colby Parkinson is off the injury report for Sunday's game against the Cardinals.
Fantasy impact: Parkinson closed the week with a full practice on Friday.
Denzel Boston (foot) is good to go for Sunday's game against the Baltimore Ravens.
Fantasy impact: The rookie will be good to go on Sunday, despite dealing with a foot injury at practice throughout the week. He has been good through the first five weeks of the season and can safely be started in most league formats at this point.
Tyler Higbee is off the injury report for Sunday's game against the Cardinals.
Fantasy impact: Higbee will be good to go despite not practicing on Friday.
Andrew Vorhees (foot) is questionable for Sunday's game against the Cleveland Browns.
Fantasy impact: Vorhees is uncertain to play on Sunday, as he's still dealing with a foot issue of some kind. If he's sidelined, the interior of Baltimore's offensive line will be weakened with Cam Jurgens (concussion) also out and Emery Jones Jr. (ankle) questionable for Week 6.
Davis Allen is off the injury report for Sunday's game against the Cardinals.
Fantasy impact: Allen remains off the fantasy radar.
Kam Curl is listed as questionable for Sunday's game against the Cardinals.
Fantasy impact: Curl did not practice on Friday. His status will need to be monitored closer to kickoff.
Blake Gillikin is listed as questionable for Sunday's game against the Rams.
Fantasy impact: Gillikin was added to the injury report on Friday.
John Simpson (groin) will be active for Sunday's game against the Cleveland Browns.
Fantasy impact: The veteran lineman will be available to play on Sunday, despite being a non-participant at Thursday's practice due to his groin issue. He should continue to be a solid starter for the Ravens moving forward.
Kitan Crawford is listed as questionable for Sunday's game against the Rams.
Fantasy impact: Crawford will have a chance to be activated from injured reserve on Sunday.
Zaven Collins is listed as questionable for Sunday's game against the Rams.
Fantasy impact: Collins was added to the injury report for Friday. His status is uncertain for Sunday.
Budda Baker is listed as questionable for Sunday's game against the Rams.
Fantasy impact: Baker did not practice on Wednesday or Friday this week. His status will need to be monitored closer to kickoff.